

If reflux is suspected this should be addressed by a qualified health professional.
This unsolicited product review may be found on Youtube through this link:
https://youtube.com/shorts/7pE-AZanp6E?si=R487b1pMhiBQWE9e
2026 individual sales on Amazon for USA customers.

An orthodontist shares insights about what his wife learned after using pH7Smile, a hydroxyapatite gel that serves as an effective retainer cleaner. She discovered how to clean your retainer more efficiently, as this product works similarly to an Invisalign cleaner, incorporating xylitol gel for added benefits.
Check out this video from Myth Buster Star Rachel Pizzolato, who has been compensated for this video. In it, she discusses effective methods on how to clean your retainer using our specially formulated hydroxyapatite gel. Many top lecturers have endorsed our products, including those who speak about the benefits of our retainer cleaner and xylitol gel. Here are a few notable experts who have either spoken about our gels or use them: 1) Janice Hurley - https://janicehurley.com/ 2) Dr. John Nosti - https://clinicalmastery.com/our-faculty/ 3) Dr. Len Tau - https://toothordare.podbean.com/e/a-glowing-review-with-dr-leonard-tau/ 4) Dr. Eric Block - https://www.thestressfreedentist.com/ 5) Dr. Leslie Laing - President of Sjogren's Society of Canada - https://www.yorkvilledental.net/meet-us. If you're looking for an effective Invisalign cleaner, our products are designed to keep your dental appliances fresh and clean.
Could YOU Be Neglecting the Rise in Decay Under Aligners and Retainers?
Acidic conditions build fast — and traditional measures do not address the highest risk of damage during the night.
As aligner therapy, such as Invisalign, becomes more popular, so does a silent but serious concern: rising enamel damage during treatment. Aligners and retainers do more than just trap plaque — they magnify the acidic environment around the teeth. Saliva can’t neutralize acids when aligners are sealed in place — especially overnight.
And while patients brush, floss, and rinse during the day, traditional measures do not address the highest risk of damage during the night. This is where pH7Smile Appliance Gels come in.
Formulated specifically for use inside aligners and retainers, pH7Smile is available in two bioactive options:
- Nano-hydroxyapatite + baking soda — for remineralization and buffering
- Xylitol + baking soda — for acid neutralization and bacterial interference
(NOTE: In 2026 we launch pH7Smile Advanced in a 100 ML pump-see the New Product page)
Both work silently while patients sleep, helping protect enamel, reduce sensitivity, and buffer acids in the very places hygiene can’t reach. If you’re not yet addressing the acid entrapment risk that aligners create, you may be overlooking a critical point of failure — and a powerful opportunity to elevate your standard of care. Our two pH7Smile gels include the original xylitol-baking soda (X for short) and the new nano-hydroxyapatite-baking soda version (HA). The xylitol-free version of pH7Smile employs a very special nano hydroxyapatite gel (nanoXIM CAREPASTE).
While there was some negative press concerning xylitol safety in June 2024, a closer look at the studies found the doses of concern were the equivalent of consuming a bottle of our gel every day. Advocates of xylitol still feel it is a worthy ingredient for dental health products as an alternative to fluoride, which some want to avoid. Our initial concerns with xylitol after reading the sensationalized headlines now appear unfounded, and lower dose xylitol products are considered safe.
Recent news:
A prominent US orthodontist university is evaluating pH7Smile for a potential study of its benefits and potential reduction of risks from clear aligner therapy. A top Sjogren's dental specialist proposes a study to substantiate the application of pH7Smile for dry mouth sufferers who have magnified dental risks.
As seen on OrthoTown.com - https://www.orthotown.com/news/details/12793/new-dental-gel-combines-xylitol-and-baking-soda-to-mimic-saliva
A discussion of xylitol and monk fruit benefits is found on the following RDH website: https://www.rdhmag.com/patient-care/article/55134326/sugar-alcohols-natural-sweeteners-and-oral-health-part-2
NOTE: Xylitol is in the original pH7Smile and Monk fruit extract is used in the Hydroxyapatite formula along with clove oil. For those wondering how to clean your retainer effectively, consider incorporating pH7Smile products into your routine.
Patients are given dental appliances every day, and even with perfect home care, various factors can turn the environment inside a dental appliance into a war zone. Studies show that a lack of saliva flow allows harmful bacteria to proliferate, overpowering the healthy strains that are crucial for oral health. It seems that the goal of eliminating nearly 100% of the 'bugs' as claimed by many dental health products, including some retainer cleaners, may lead to negative health side effects, such as an increased risk of diabetes. Our two product versions of pH7Smile incorporate a patented combination of natural ingredients, including baking soda, to reduce harmful bacteria and help control acidity. For those wondering how to clean your retainer effectively, consider using hydroxyapatite gel or an Invisalign cleaner for optimal results. Additionally, xylitol gel can further enhance your dental hygiene routine. Interested in more studies that support concerns with wearing unprotected dental appliances? Visit our sister webpage: https://retainergel.com/studies. The dangers of dental appliances are becoming increasingly clear, especially with findings from 2024 revealing that teeth can decay during clear aligner treatment (https://www.drbicuspid.com/dental-specialties/orthodontics/invisible-aligners/article/15670101/white-spot-lesions-are-common-in-adolescent-aligner-patients) and further consequences of poor homecare and bad habits during aligner therapy (https://smilesaintlouis.com/wp-content/uploads/2021/09/consequences-poor-hygiene.pdf?). For more insights, check out the Mayo Clinic's information on dry mouth causes (https://www.mayoclinic.org/diseases-conditions/dry-mouth/symptoms-causes/syc-20356048).
Millions of people are instructed to wear dental appliances including clear aligners like Invisalign and Clear Correct, orthodontic retainers, bruxism splints or night guards, orthotics, TMJ appliances, snoring and apnea dental appliances, protective clear trays, removable dentures or implant prosthetics, snap-on smiles, and even celebrity grills or removable gold teeth.
Patients often deal with various medical conditions that increase acidity and dry mouth, which heightens the importance of considering not just the blockage of normal saliva flow but also the protection from less than ideal conditions. To maintain your dental appliances, especially when using an Invisalign cleaner or a retainer cleaner, one effective method is to apply hydroxyapatite gel. This can help keep your aligners clean and safe for use. Additionally, for those using retainers, learning how to clean your retainer with xylitol gel can enhance oral hygiene while preventing bacteria buildup.
Simply apply the gel to the inside of your appliance, wear it as usual, spit out any excess, and rinse with cold water in the morning or as otherwise directed.
The dental harm from acid reflux can occur even in people with excellent home care. Many do not even know they have the condition, and when wearing an appliance like a retainer or Invisalign, stomach acids can slip underneath and damage the teeth. To combat this, knowing how to clean your retainer is essential. Our baking soda formulation, in combination with our hydroxyapatite gel and xylitol gel, helps to neutralize acidity and maintain a pH of 7 inside the appliance, ensuring a healthier environment for your teeth. Using a dedicated retainer cleaner or Invisalign cleaner can further protect your oral health.
Hundreds of medications and recreational drugs, such as marijuana, can lead to dry mouth, which increases the risk of tooth decay. Various medical conditions, including Sjogren's syndrome and diabetes, as well as the natural aging process, contribute to this issue. To combat dry mouth, the optimized natural additives and baking soda in our product work perfectly alongside a typical regimen of high fluoride toothpaste, brushing, flossing, and tongue scraping. Additionally, mouth breathing also results in a dry mouth and lowers the pH into the acidic zone, according to a recent study, further increasing the risk of tooth decay. To maintain oral hygiene, especially for those using Invisalign, it's important to know how to clean your retainer effectively. Our hydroxyapatite gel and xylitol gel are excellent options for an effective retainer cleaner, ensuring your dental appliances stay fresh and free from harmful bacteria. For more on this topic, you can refer to this study: https://www.researchgate.net/publication/287204150_Intraoral_pH_and_temperature_during_sleep_with_and_without_mouth_breathing.
Radiation and chemotherapy often disrupt the natural production of saliva and the body's defense systems. To support oral health, you can use protective appliances designed for pH7Smile, and any existing appliances can essentially be transformed into protective carriers of our hydroxyapatite gel. Additionally, knowing how to clean your retainer properly is crucial, and utilizing an Invisalign cleaner or a retainer cleaner that includes xylitol gel can be beneficial.
Various eating disorders often involve vomiting and serious dental complications. To mitigate harm, one potential solution is pH7Smile, which features extended clear trays that physically and chemically shield the teeth from acid exposure. Additionally, knowing how to clean your retainer is crucial, and using a retainer cleaner like hydroxyapatite gel can help maintain oral health. For those using Invisalign, an Invisalign cleaner or xylitol gel can be effective alternatives.
If you are a patient whose dental professional does not provide this product, you can order pH7Smile without a prescription. However, it is recommended that you discuss your situation with your trusted health professional. Check out our new whitening gel, which is perfect for maintaining your smile! If you're looking for tips on how to clean your retainer or searching for an effective Invisalign cleaner, our hydrating hydroxyapatite gel and xylitol gel can help keep your orthodontic devices fresh.
*Our original gel 'Retainer Gel' (baking soda-xylitol formula) was selected as one of the 'BEST NEW PRODUCTS' by Clinicians Report, a respected independent reviewer of dental products.
DISCLAIMER: Any implied health claims are not verified by health regulatory bodies. This product is currently listed as a cosmetic/breath freshening agent and is not a treatment for any illness or disease. Use should be under the supervision of a trusted dental or medical professional. The pH of the products is in the range of pH 7-8. Formulation may vary slightly from images posted and may change without notice.
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